It is to understand the specific relationship of genes, nerves, brain system and the communication strategy.

A Bridge Impersonating the PX-RICS

Neuroscience research, art therapy

2017

 

It is to understand the specific relationship of genes, nerves, brain system and the communication strategy. Then using another way to mimic the way of communication. Perhaps in the project could see something out of expectation and cannot predict the final result. Bring the Autism and strangers together by using digital media to share their thoughts and have a common topic to communicate with each other. Then express their respond by drawing the same topic.


Introduction

Autism Spectrum Disorder, as known as Autism Disorder or Asperger’s Disorder. The word “spectrum” added to it in 2013, in the latest version, Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), edited by the American Psychiatric Association. The manual is a universal authority for psychiatric diagnoses. According to the DSM-5, the Autism Spectrum is a disorder which defined by behaviours, not an intelligence quotient or physical strategies. There are two specific behavioural criteria, first is the social communication & social interaction; second is the restricted, repetitive behaviour, interests & activities.[1]


The project is working on a large but also specific area. The main purpose is to study on the Autism Spectrum Disorder communication and interaction behaviours. Yet, to have a well understanding of how Autism people have the communication problem is to study on neurobiology in the brain system and the chemical reaction inside the brain, gene and chromosome.

​My artwork and study based on a research of Tokyo University scholars paper on 16 March 2016[2]. However, to exactly understand different professional wordings or specific terms, there is much more work to study in every term by reading through the other articles and watch more videos.

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[1]American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.

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[2]Nakamura, T., Arima-Yoshida, F., Sakaue, F., Nasu-Nishimura, Y., Takeda, Y., Matsuura, K., . . . Akiyama, T. (2016, March 16). PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAAreceptor trafficking. Retrieved December 09, 2017, from https://www.nature.com/articles/ncomms10861#f1

Art concept

It is to understand the specific relationship between genes, nerves, brain system and the communication strategy. Then using another way to mimic the way of communication. Perhaps in the project could see something out of expectation and cannot predict the final result. Bring the Autism and strangers together by using digital media to share their thoughts and have a common topic to communicate with each other. Then express their respond by drawing the same topic.


Science explanation

PX-RICS is a kind of proteins which discover terminal detection of the long arm of chromosome 11. And it is also main function related to cognitive neuro performance of the brain system only. Moreover, there is a receptor called “GABA(A)”(γ-Aminobutyric acid) which mainly a Aminobutyric acid to reduce or balance the information (sound, image) from the outer world (physical environment). The problem occurred in Autism brain or the nervous system is lack of or disappear of the PX-RICS. PX-RICS just like a truck, help our brain to carry the receptor GABA(A) from one nerve to another one. As between nerves, there are some gaps called “synapses”. To transfer the receptor through synapse, there must be something could carry it. And while Autism do not have the PX-RICS, their brain would get overload, lots of information goes into their brain in the same time. This problem make them could not get the exactly information at that particular moment.

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